This article exposes the main reforms at the level of decentralization and autonomy in the Plurinational State of Bolivia. It is identified that the changes and transformations at the central level of the state towards greater decentralization, historically were due to political pressure from actors and institutions at the regional and departmental level. In democracy since 1982, there are at least two important reform periods, the first between 1994 and 1995 with the Popular Participation Law at the local government level and the Decentralization Law. The second important moment occurred with the constitutional reform and the new Political Constitution of the State in 2009 and the Andrés Ibañez Autonomy and Decentralization Framework Law in 2010. From the balance of a decade of deepening of the autonomous process, it is shown that it is still incomplete and imperfect, which suggests that Bolivia has all the characteristics of being a politically and administratively centralized country. Finally, two stylized facts related to electoral reforms and the political participation of women in this entire transformation process are analyzed.