This book investigates the historical antecedents of corruption in Mexico, the starting point is the Spanish conquest of the town of Tenochtitlan in 1521. In addition, it reveals aspects of corruption in Mexico: its origin, some of its causes, consequences , as well as some studies on perception, in order to better understand this problem; In addition, it proposes strategies for the prevention and control of corruption. After five centuries of corruption in Mexico, it is important to do a retrospective to reflect and understand how we got here. The book offers a point of view based on prevention supported by Public Ethics, a discipline that focuses on the conduct of public servants.